Palindromic Sequence Artifacts Generated during Next Generation Sequencing Library Preparation from Historic and Ancient DNA

Degradation-specific processes and variation in laboratory protocols can bias the DNA sequence composition from samples of ancient or historic origin. Here, we identify a novel artifact in sequences from historic samples of Atlantic cod (Gadus morhua), which forms interrupted palindromes consisting...

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Main Authors: Star, Bastiaan, Nederbragt, Alexander J., Hansen, Marianne H. S., Skage, Morten, Gilfillan, Gregor D., Bradbury, Ian R., Pampoulie, Christophe, Stenseth, Nils Chr, Jakobsen, Kjetill S., Jentoft, Sissel
פורמט: Artigo
שפה:Inglês
יצא לאור: Public Library of Science 2014
נושאים:
Research Article
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3946424/
https://ncbi.nlm.nih.gov/pubmed/24608104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0089676
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