Gambiense Human African Trypanosomiasis and Immunological Memory: Effect on Phenotypic Lymphocyte Profiles and Humoral Immunity

In mice, experimental infection with Trypanosoma brucei causes decreased bone marrow B-cell development, abolished splenic B-cell maturation and loss of antibody mediated protection including vaccine induced memory responses. Nothing is known about this phenomenon in human African trypanosomiasis (H...

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Hlavní autoři: Lejon, Veerle, Mumba Ngoyi, Dieudonné, Kestens, Luc, Boel, Luc, Barbé, Barbara, Kande Betu, Victor, van Griensven, Johan, Bottieau, Emmanuel, Muyembe Tamfum, Jean-Jacques, Jacobs, Jan, Büscher, Philippe
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2014
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3946376/
https://ncbi.nlm.nih.gov/pubmed/24603894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1003947
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