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A Prime Time for Trained Immunity: Innate Immune Memory in Newborns & Infants

The newborn and infant periods of early life are associated with heightened vulnerability to infection. Limited antigen exposure and distinct adaptive immune function compared to the adult places a greater burden on innate immunity for host defense to microbial challenge during this time. Trained im...

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Detalhes bibliográficos
Main Authors: Levy, Ofer, Wynn, James L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3946366/
https://ncbi.nlm.nih.gov/pubmed/24356292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000356035
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