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Development of Novel Tumor-Targeted Theranostic Nanoparticles Activated by Membrane-Type Matrix Metalloproteinases for Combined Cancer Magnetic Resonance Imaging and Therapy

A major drawback with current cancer therapy is the prevalence of unrequired dose-limiting toxicity to non-cancerous tissues and organs, which is further compounded by a limited ability to rapidly and easily monitor drug delivery, pharmacodynamics and therapeutic response. In this report, we describ...

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Detalhes bibliográficos
Main Authors: Ansari, Celina, Tikhomirov, Grigory A., Hong, Su Hyun, Falconer, Robert A., Loadman, Paul M., Gill, Jason H., Castaneda, Rosalinda, Hazard, Florette K., Tong, Ling, Lenkov, Olga D., Felsher, Dean W., Rao, Jianghong, Daldrup-Link, Heike E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3946335/
https://ncbi.nlm.nih.gov/pubmed/24038954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/smll.201301456
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