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A synthetic, chemically modified ribozyme eliminates amelogenin, the major translation product in developing mouse enamel in vivo.

Ribozymes are small RNA structures capable of cleaving RNA target molecules in a catalytic fashion. Designed ribozymes can be targeted to specific mRNAs, blocking their expression without affecting normal functions of other genes. Because of their specific and catalytic mode of action ribozymes are...

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Detalhes bibliográficos
Main Authors: Lyngstadaas, S P, Risnes, S, Sproat, B S, Thrane, P S, Prydz, H P
Formato: Artigo
Idioma:Inglês
Publicado em: 1995
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC394632/
https://ncbi.nlm.nih.gov/pubmed/7489712
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