RAS mutations in early age leukaemia modulated by NQO1 rs1800566 (C609T) are associated with second-hand smoking exposures

BACKGROUND: Deregulation of the MAPK genes signalling caused by somatic mutations have been implied in leukaemia pathogenesis, including RAS mutation (RAS(mut)) in acute myeloid leukaemia (AML), which has been associated with intra-uterine chemical exposures. A case-case study was conducted in order...

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Detalhes bibliográficos
Main Authors: Andrade, Francianne Gomes, Furtado-Silva, Juliana Montibeller, Gonçalves, Bruno Alves de Aguiar, Thuler, Luiz Claudio Santos, Barbosa, Thayana Conceição, Emerenciano, Mariana, Siqueira, André, Pombo-de-Oliveira, Maria S
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3946262/
https://ncbi.nlm.nih.gov/pubmed/24571676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-14-133
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