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Bisphosphonamidate Clodronate Prodrug Exhibits Selective Cytotoxic Activity Against Melanoma Cell Lines

Bisphosphonates are used clinically to treat disorders of calcium metabolism and malignant bone disease and are known to inhibit cancer cell growth, adhesion, and invasion. However, clinical use of these agents for the treatment of extraskeletal disease is limited due to low cell permeability. We re...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Webster, Marie R., Kamat, Chandrashekhar, Connis, Nick, Zhao, Ming, Weeraratna, Ashani T., Rudek, Michelle A., Hann, Christine L., Freel Meyers, Caren L.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: 2013
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3945958/
https://ncbi.nlm.nih.gov/pubmed/24310621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-13-0315
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