High-throughput sequencing reveals the disruption of methylation of imprinted gene in induced pluripotent stem cells

It remains controversial whether the abnormal epigenetic modifications accumulated in the induced pluripotent stem cells (iPSCs) can ultimately affect iPSC pluripotency. To probe this question, iPSC lines with the same genetic background and proviral integration sites were established, and the pluri...

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Detalhes bibliográficos
Main Authors: Chang, Gang, Gao, Shuai, Hou, Xinfeng, Xu, Zijian, Liu, Yanfeng, Kang, Lan, Tao, Yu, Liu, Wenqiang, Huang, Bo, Kou, Xiaochen, Chen, Jiayu, An, Lei, Miao, Kai, Di, Keqian, Wang, Zhilong, Tan, Kun, Cheng, Tao, Cai, Tao, Gao, Shaorong, Tian, Jianhui
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3945885/
https://ncbi.nlm.nih.gov/pubmed/24381111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2013.173
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