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Opening paths to novel analgesics: the role of potassium channels in chronic pain

Chronic pain is associated with abnormal excitability of the somatosensory system and remains poorly treated in the clinic. Potassium (K(+)) channels are crucial determinants of neuronal activity throughout the nervous system. Opening of these channels facilitates a hyperpolarizing K(+) efflux acros...

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Autori principali: Tsantoulas, Christoforos, McMahon, Stephen B.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier Applied Science Publishing 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3945816/
https://ncbi.nlm.nih.gov/pubmed/24461875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tins.2013.12.002
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