High calcium concentration in bones promotes bone metastasis in renal cell carcinomas expressing calcium-sensing receptor

BACKGROUND: The prognosis for renal cell carcinoma (RCC) is related to a high rate of metastasis, including 30% of bone metastasis. Characteristic for bone tissue is a high concentration of calcium ions. In this study, we show a promoting effect of an enhanced extracellular calcium concentration on...

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Detalhes bibliográficos
Principais autores: Joeckel, Elke, Haber, Tobias, Prawitt, Dirk, Junker, Kerstin, Hampel, Christian, Thüroff, Joachim W, Roos, Frederik C, Brenner, Walburgis
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3945739/
https://ncbi.nlm.nih.gov/pubmed/24576174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-13-42
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