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Inflammatory and cytotoxic effects of acrolein, nicotine, acetylaldehyde and cigarette smoke extract on human nasal epithelial cells

BACKGROUND: Cigarette smoke induces a pro-inflammatory response in airway epithelial cells but it is not clear which of the various chemicals contained within cigarette smoke (CS) should be regarded as predominantly responsible for these effects. We hypothesised that acrolein, nicotine and acetylald...

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Detalhes bibliográficos
Main Authors: Comer, David M, Elborn, Joseph Stuart, Ennis, Madeleine
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3945717/
https://ncbi.nlm.nih.gov/pubmed/24581246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2466-14-32
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