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Selection of novel Mg(2+)-dependent self-cleaving ribozymes.

Four RNA motifs are known that catalyse site-specific cleavage in the presence of Mg2+ ions, all discovered in natural RNAs. In a single in vitro selection experiment we have isolated representatives of five novel classes of Mg(2+)-dependent ribozymes. Small versions of three of these showed that a...

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Detalhes bibliográficos
Publicado no:EMBO J
Main Authors: Williams, K P, Ciafré, S, Tocchini-Valentini, G P
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 1995
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC394547/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7556098/
https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1995.tb00134.x
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