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LILRB2 Interaction with HLA Class I Correlates with Control of HIV-1 Infection

Natural progression of HIV-1 infection depends on genetic variation in the human major histocompatibility complex (MHC) class I locus, and the CD8(+) T cell response is thought to be a primary mechanism of this effect. However, polymorphism within the MHC may also alter innate immune activity agains...

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Hauptverfasser: Bashirova, Arman A., Martin-Gayo, Enrique, Jones, Des C., Qi, Ying, Apps, Richard, Gao, Xiaojiang, Burke, Patrick S., Taylor, Craig J., Rogich, Jerome, Wolinsky, Steven, Bream, Jay H., Duggal, Priya, Hussain, Shehnaz, Martinson, Jeremy, Weintrob, Amy, Kirk, Gregory D., Fellay, Jacques, Buchbinder, Susan P., Goedert, James J., Deeks, Steven G., Pereyra, Florencia, Trowsdale, John, Lichterfeld, Mathias, Telenti, Amalio, Walker, Bruce D., Allen, Rachel L., Carrington, Mary, Yu, Xu G.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2014
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3945438/
https://ncbi.nlm.nih.gov/pubmed/24603468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1004196
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