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Signal transduction by the alpha 6 beta 4 integrin: distinct beta 4 subunit sites mediate recruitment of Shc/Grb2 and association with the cytoskeleton of hemidesmosomes.

We have examined the mechanism of signal transduction by the hemidesmosomal integrin alpha 6 beta 4, a laminin receptor involved in morphogenesis and tumor progression. Immunoprecipitation and immune complex kinase assays indicated that antibody- or laminin-induced ligation of alpha 6 beta 4 causes...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Mainiero, F, Pepe, A, Wary, K K, Spinardi, L, Mohammadi, M, Schlessinger, J, Giancotti, F G
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 1995
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC394539/
https://ncbi.nlm.nih.gov/pubmed/7556090
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