Histone Deacetylase Inhibitors Modulate the Transcriptional Regulation of Guanylyl Cyclase/Natriuretic Peptide Receptor-A Gene: INTERACTIVE ROLES OF MODIFIED HISTONES, HISTONE ACETYLTRANSFERASE, p300, AND Sp1

Atrial natriuretic peptide (ANP) binds guanylyl cyclase-A/natriuretic peptide receptor-A (GC-A/NPRA) and produces the intracellular second messenger, cGMP, which regulates cardiovascular homeostasis. We sought to determine the function of histone deacetylases (HDACs) in regulating Npr1 (coding for G...

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Hauptverfasser: Kumar, Prerna, Tripathi, Satyabha, Pandey, Kailash N.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2014
Schlagworte:
Gene Regulation
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3945360/
https://ncbi.nlm.nih.gov/pubmed/24451378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.511444
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