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Negative feedback regulation of wild-type p53 biosynthesis.

When growth-arrested mouse fibroblasts re-entered the cell-cycle, the rise in tumour suppressor p53 mRNA level markedly preceded the rise in expression of the p53 protein. Furthermore, gamma-irradiation of such cells led to a rapid increase in p53 protein biosynthesis even in the presence of the tra...

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Bibliografiske detaljer
Main Authors: Mosner, J, Mummenbrauer, T, Bauer, C, Sczakiel, G, Grosse, F, Deppert, W
Format: Artigo
Sprog:Inglês
Udgivet: 1995
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC394536/
https://ncbi.nlm.nih.gov/pubmed/7556087
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