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The Novel Secreted Adipokine WNT1-inducible Signaling Pathway Protein 2 (WISP2) Is a Mesenchymal Cell Activator of Canonical WNT

WNT1-inducible-signaling pathway protein 2 (WISP2) is primarily expressed in mesenchymal stem cells, fibroblasts, and adipogenic precursor cells. It is both a secreted and cytosolic protein, the latter regulating precursor cell adipogenic commitment and PPARγ induction by BMP4. To examine the effect...

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Autors principals: Grünberg, John R., Hammarstedt, Ann, Hedjazifar, Shahram, Smith, Ulf
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3945351/
https://ncbi.nlm.nih.gov/pubmed/24451367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.511964
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