The Expression of Fn14 via Mechanical Stress-activated JNK Contributes to Apoptosis Induction in Osteoblasts

Bone mass is maintained by the balance between the activities of bone-forming osteoblasts and bone-resorbing osteoclasts. It is well known that adequate mechanical stress is essential for the maintenance of bone mass, whereas excess mechanical stress induces bone resorption. However, it has not been...

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Main Authors: Matsui, Hiroyuki, Fukuno, Naoto, Kanda, Yoshiaki, Kantoh, Yusuke, Chida, Toko, Nagaura, Yuko, Suzuki, Osamu, Nishitoh, Hideki, Takeda, Kohsuke, Ichijo, Hidenori, Sawada, Yasuhiro, Sasaki, Keiichi, Kobayashi, Takayasu, Tamura, Shinri
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2014
Teme:
Signal Transduction
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3945310/
https://ncbi.nlm.nih.gov/pubmed/24446436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.536300
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