Down-regulated Peroxisome Proliferator-activated Receptor γ (PPARγ) in Lung Epithelial Cells Promotes a PPARγ Agonist-reversible Proinflammatory Phenotype in Chronic Obstructive Pulmonary Disease (COPD)

Chronic obstructive pulmonary disease (COPD) is a progressive inflammatory condition and a leading cause of death, with no available cure. We assessed the actions in pulmonary epithelial cells of peroxisome proliferator-activated receptor γ (PPARγ), a nuclear hormone receptor with anti-inflammatory...

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Detalhes bibliográficos
Main Authors: Lakshmi, Sowmya P., Reddy, Aravind T., Zhang, Yingze, Sciurba, Frank C., Mallampalli, Rama K., Duncan, Steven R., Reddy, Raju C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Molecular Bases of Disease
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3945305/
https://ncbi.nlm.nih.gov/pubmed/24368768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.536805
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