GC-Rich DNA Elements Enable Replication Origin Activity in the Methylotrophic Yeast Pichia pastoris

The well-studied DNA replication origins of the model budding and fission yeasts are A/T-rich elements. However, unlike their yeast counterparts, both plant and metazoan origins are G/C-rich and are associated with transcription start sites. Here we show that an industrially important methylotrophic...

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Autores principales: Liachko, Ivan, Youngblood, Rachel A., Tsui, Kyle, Bubb, Kerry L., Queitsch, Christine, Raghuraman, M. K., Nislow, Corey, Brewer, Bonita J., Dunham, Maitreya J.
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3945215/
https://ncbi.nlm.nih.gov/pubmed/24603708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1004169
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