Final Pre-40S Maturation Depends on the Functional Integrity of the 60S Subunit Ribosomal Protein L3

Ribosomal protein L3 is an evolutionarily conserved protein that participates in the assembly of early pre-60S particles. We report that the rpl3[W255C] allele, which affects the affinity and function of translation elongation factors, impairs cytoplasmic maturation of 20S pre-rRNA. This was not see...

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Main Authors: García-Gómez, Juan J., Fernández-Pevida, Antonio, Lebaron, Simon, Rosado, Iván V., Tollervey, David, Kressler, Dieter, de la Cruz, Jesús
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2014
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3945201/
https://ncbi.nlm.nih.gov/pubmed/24603549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1004205
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