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The Rate of Nonallelic Homologous Recombination in Males Is Highly Variable, Correlated between Monozygotic Twins and Independent of Age

Nonallelic homologous recombination (NAHR) between highly similar duplicated sequences generates chromosomal deletions, duplications and inversions, which can cause diverse genetic disorders. Little is known about interindividual variation in NAHR rates and the factors that influence this. We estima...

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Detalhes bibliográficos
Main Authors: MacArthur, Jacqueline A. L., Spector, Timothy D., Lindsay, Sarah J., Mangino, Massimo, Gill, Raj, Small, Kerrin S., Hurles, Matthew E.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3945173/
https://ncbi.nlm.nih.gov/pubmed/24603440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1004195
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