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CD247 Modulates Blood Pressure by Altering T Lymphocyte Infiltration in the Kidney

The CD3 zeta chain (CD247), a gene involved in T cell signaling, has been shown to associate with blood pressure in human genetic studies. To test the functional role of CD247 in hypertension and renal disease, zinc-finger nucleases targeting CD247 were injected into Dahl SS/JrHsdMcwi embryos. The r...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Rudemiller, Nathan, Lund, Hayley, Jacob, Howard J., Geurts, Aron M, Mattson, David L.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2013
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3945169/
https://ncbi.nlm.nih.gov/pubmed/24343121
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.113.02191
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