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CD247 Modulates Blood Pressure by Altering T Lymphocyte Infiltration in the Kidney
The CD3 zeta chain (CD247), a gene involved in T cell signaling, has been shown to associate with blood pressure in human genetic studies. To test the functional role of CD247 in hypertension and renal disease, zinc-finger nucleases targeting CD247 were injected into Dahl SS/JrHsdMcwi embryos. The r...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3945169/ https://ncbi.nlm.nih.gov/pubmed/24343121 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.113.02191 |
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