Preventive Effects of a Kampo Medicine, Kakkonto, on Inflammatory Responses via the Suppression of Extracellular Signal-Regulated Kinase Phosphorylation in Lipopolysaccharide-Treated Human Gingival Fibroblasts

Periodontal disease is accompanied by inflammation of the gingiva and destruction of periodontal tissues, leading to alveolar bone loss in severe clinical cases. The chemical mediator prostaglandin E(2) (PGE(2)) and cytokines such as interleukin- (IL-)6 and IL-8 have been known to play important rol...

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Autors principals: Kitamura, Hiroyuki, Urano, Hiroko, Ara, Toshiaki
Format: Artigo
Idioma:Inglês
Publicat: Hindawi Publishing Corporation 2014
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3945151/
https://ncbi.nlm.nih.gov/pubmed/24693448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/784019
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