Expression Level and Subcellular Localization of Heme Oxygenase-1 Modulates Its Cytoprotective Properties in Response to Lung Injury: A Mouse Model

Premature infants exposed to hyperoxia suffer acute and long-term pulmonary consequences. Nevertheless, neonates survive hyperoxia better than adults. The factors contributing to neonatal hyperoxic tolerance are not fully elucidated. In contrast to adults, heme oxygenase (HO)-1, an endoplasmic retic...

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Main Authors: Namba, Fumihiko, Go, Hayato, Murphy, Jennifer A., La, Ping, Yang, Guang, Sengupta, Shaon, Fernando, Amal P., Yohannes, Mekdes, Biswas, Chhanda, Wehrli, Suzanne L., Dennery, Phyllis A.
格式: Artigo
語言:Inglês
出版: Public Library of Science 2014
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3944979/
https://ncbi.nlm.nih.gov/pubmed/24599172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0090936
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