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A Halotyrosine Antibody that Detects Increased Protein Modifications in Asthma Patients

Airway inflammation has a pathophysiological role in asthma. Eosinophils, which are commonly increased in asthmatic airways, express eosinophil peroxidase and thereby produce hypobromite and bromotyrosine. Bromotyrosine is believed to be a specific marker for eosinophil activity, but developing an a...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Jin, Hongjun, Hallstrand, Teal S., Daly, Don S., Matzke, Melissa M., Nair, Parameswaran, Bigelow, Diana J., Pounds, Joel G., Zangar, Richard C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3944894/
https://ncbi.nlm.nih.gov/pubmed/24295867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jim.2013.11.013
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