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The Copper-Responsive RicR Regulon Contributes to Mycobacterium tuberculosis Virulence

As with most life on Earth, the transition metal copper (Cu) is essential for the viability of the human pathogen Mycobacterium tuberculosis. However, infected hosts can also use Cu to control microbial growth. Several Cu-responsive pathways are present in M. tuberculosis, including the regulated in...

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Detalhes bibliográficos
Main Authors: Shi, Xiaoshan, Festa, Richard A., Ioerger, Thomas R., Butler-Wu, Susan, Sacchettini, James C., Darwin, K. Heran, Samanovic, Marie I.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Microbiology 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3944814/
https://ncbi.nlm.nih.gov/pubmed/24549843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.00876-13
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