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Botulinum Toxin Suppression of CNS Network Activity In Vitro

The botulinum toxins are potent agents which disrupt synaptic transmission. While the standard method for BoNT detection and quantification is based on the mouse lethality assay, we have examined whether alterations in cultured neuronal network activity can be used to detect the functional effects o...

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Detalhes bibliográficos
Main Authors: Pancrazio, Joseph J., Gopal, Kamakshi, Keefer, Edward W., Gross, Guenter W.
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3944787/
https://ncbi.nlm.nih.gov/pubmed/24688538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/732913
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