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Expression of the Murine Norovirus (MNV) ORF1 Polyprotein Is Sufficient to Induce Apoptosis in a Virus-Free Cell Model

Investigations into human norovirus infection, replication and pathogenesis, as well as the development of potential antiviral agents, have been restricted by the lack of a cell culture system for human norovirus. To date, the optimal cell culture surrogate virus model for studying human norovirus b...

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Bibliografiske detaljer
Main Authors: Herod, Morgan R., Salim, Omar, Skilton, Rachel J., Prince, Cynthia A., Ward, Vernon K., Lambden, Paul R., Clarke, Ian N.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3944349/
https://ncbi.nlm.nih.gov/pubmed/24599381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0090679
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