Clinical Assessment of a Novel Recombinant Simian Adenovirus ChAdOx1 as a Vectored Vaccine Expressing Conserved Influenza A Antigens

Adenoviruses are potent vectors for inducing and boosting cellular immunity to encoded recombinant antigens. However, the widespread seroprevalence of neutralizing antibodies to common human adenovirus serotypes limits their use. Simian adenoviruses do not suffer from the same drawbacks. We have con...

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Bibliografiske detaljer
Main Authors: Antrobus, Richard D, Coughlan, Lynda, Berthoud, Tamara K, Dicks, Matthew D, Hill, Adrian VS, Lambe, Teresa, Gilbert, Sarah C
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2014
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Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3944330/
https://ncbi.nlm.nih.gov/pubmed/24374965
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2013.284
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