A functional role for Smad7 in sustaining colon cancer cell growth and survival

Initially identified as an inhibitor of transforming growth factor (TGF)-β mainly owing to its ability to bind TGF-β receptor type I and abrogate TGF-β-driven signaling, Smad7 can interact with additional intracellular proteins and regulate TGF-β-independent pathways, thus having a key role in the c...

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Detalhes bibliográficos
Main Authors: Stolfi, C, De Simone, V, Colantoni, A, Franzè, E, Ribichini, E, Fantini, M C, Caruso, R, Monteleone, I, Sica, G S, Sileri, P, MacDonald, T T, Pallone, F, Monteleone, G
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3944263/
https://ncbi.nlm.nih.gov/pubmed/24556688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2014.49
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