MicroRNA-21 regulates T-cell apoptosis by directly targeting the tumor suppressor gene Tipe2

MicroRNAs (MiRs) are short noncoding RNAs that can regulate gene expression. It has been reported that miR-21 suppresses apoptosis in activated T cells, but the molecular mechanism remains undefined. Tumor suppressor Tipe2 (or tumor necrosis factor-α-induced protein 8 (TNFAIP8)-like 2 (TNFAIP8L2)) i...

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Detalhes bibliográficos
Main Authors: Ruan, Q, Wang, P, Wang, T, Qi, J, Wei, M, Wang, S, Fan, T, Johnson, D, Wan, X, Shi, W, Sun, H, Chen, Y H
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3944261/
https://ncbi.nlm.nih.gov/pubmed/24577093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2014.47
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