Expression of base excision repair key factors and miR17 in familial and sporadic breast cancer

Understanding of BRCA1/2 interaction with the base excision repair (BER) pathway could improve therapy based on ‘synthetic lethality', whose effectiveness is based on homologous recombination deficiency in cells lacking functional BRCA genes. However, poly (ADP-ribose) polymerase (PARP) inhibit...

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Detalhes bibliográficos
Main Authors: De Summa, S, Pinto, R, Pilato, B, Sambiasi, D, Porcelli, L, Guida, G, Mattioli, E, Paradiso, A, Merla, G, Micale, L, De Nittis, P, Tommasi, S
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3944247/
https://ncbi.nlm.nih.gov/pubmed/24556691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2014.30
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