Blockade of BFA-mediated apoptosis in macrophages by the HIV-1 Nef protein

HIV-1 Nef protein has key roles at almost all stages of the viral life cycle. We assessed the role of Nef and of the translation elongation factor eEF1A in primary human macrophages. Nuclear retention experiments and inhibition of the exportin-t (Exp-t) pathway suggested that cytoplasmic relocalizat...

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Autores principales: Abbas, W, Khan, K A, Kumar, A, Tripathy, M K, Dichamp, I, Keita, M, Mahlknecht, U, Rohr, O, Herbein, G
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2014
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Original Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3944234/
https://ncbi.nlm.nih.gov/pubmed/24556695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2014.16
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