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The coactivator p15 (PC4) initiates transcriptional activation during TFIIA-TFIID-promoter complex formation.

We have analyzed the mechanisms underlying stimulation of transcription by the activator GAL4-AH and the recombinant coactivator p15 (PC4). We show that p15 binds to both double-stranded and single-stranded DNA. Analyses of deletion mutants correlates binding to double-stranded DNA with the ability...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Kaiser, K, Stelzer, G, Meisterernst, M
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1995
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC394420/
https://ncbi.nlm.nih.gov/pubmed/7628453
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