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A direct and non-redundant role for thymic stromal lymphopoietin on anti-viral CD8 T cell responses in the respiratory mucosa

Mucosally produced thymic stromal lymphopoietin (TSLP) regulates Th2 responses by signaling to DCs and CD4 T cells. Activated CD8 T cells express the TSLP receptor (TSLP-R), yet a direct role for TSLP in CD8 T cell immunity in the mucosa has not been described. Since TSLP shares signaling components...

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Detalhes bibliográficos
Main Authors: Shane, Hillary L., Klonowski, Kimberly D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3943877/
https://ncbi.nlm.nih.gov/pubmed/24489089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1302085
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