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Endothelin-1 receptor A blocker darusentan decreased hepatic changes and improved liver repopulation after cell transplantation in rats
Cell transplantation-induced hepatic ischemia and recruitment of vasoconstrictors, e.g., endothelin-1, leads to clearance of transplanted cells and poses problems for liver repopulation. Therefore, we determined whether darusentan, which potently blocks endothelin-1 receptor type A, could benefit ce...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3943745/ https://ncbi.nlm.nih.gov/pubmed/24114775 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.26766 |
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