Tailored Glycopolymers as Anticoagulant Heparin Mimetics

Heparin and its low molecular weight derivatives are clinical therapeutics used to treat and prevent blood clots, but are prone to side effects and contamination. Here we describe the design and expedient synthesis of heparin-based glycopolymers that are potent and potentially safer mimetics of hepa...

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Bibliografiske detaljer
Main Authors: Oh, Young In, Sheng, Gloria J., Chang, Shuh-Kuen, Hsieh-Wilson, Linda C.
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3943734/
https://ncbi.nlm.nih.gov/pubmed/24123787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201306968
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