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Tailored Glycopolymers as Anticoagulant Heparin Mimetics

Heparin and its low molecular weight derivatives are clinical therapeutics used to treat and prevent blood clots, but are prone to side effects and contamination. Here we describe the design and expedient synthesis of heparin-based glycopolymers that are potent and potentially safer mimetics of hepa...

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Detalhes bibliográficos
Principais autores: Oh, Young In, Sheng, Gloria J., Chang, Shuh-Kuen, Hsieh-Wilson, Linda C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3943734/
https://ncbi.nlm.nih.gov/pubmed/24123787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201306968
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