A Sensitive and Robust HPLC Assay with Fluorescence Detection for the Quantification of Pomalidomide in Human Plasma for Pharmacokinetic Analyses

Pomalidomide is a second generation IMiD (immunomodulatory agent) that has recently been granted approval by the Food and Drug Administration for treatment of relapsed multiple myeloma after prior treatment with two antimyeloma agents, including lenalidomide and bortezomib. A simple and robust HPLC...

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Main Authors: Shahbazi, Shandiz, Peer, Cody J., Polizzotto, Mark N., Uldrick, Thomas S., Roth, Jeffrey, Wyvill, Kathleen M., Aleman, Karen, Zeldis, Jerome B., Yarchoan, Robert, Figg, William D.
Format: Artigo
Sprog:Inglês
Udgivet: 2014
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3943695/
https://ncbi.nlm.nih.gov/pubmed/24486861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jpba.2014.01.001
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