Mutations in the Feline Immunodeficiency Virus Envelope Glycoprotein Confer Resistance to a Dominant-Negative Fragment of Tsg101 by Enhancing Infectivity and Cell-to-Cell Virus Transmission

The Pro-Ser-Ala-Pro (PSAP) motif in the p2 domain of feline immunodeficiency virus (FIV) Gag is required for efficient virus release, virus replication, and Gag binding to the ubiquitin-E2-variant (UEV) domain of Tsg101. As a result of this direct interaction, expression of an N-terminal fragment of...

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Huvudupphovsmän: Luttge, Benjamin G., Panchal, Prashant, Puri, Vinita, Checkley, Mary Ann, Freed, Eric O.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2013
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3943682/
https://ncbi.nlm.nih.gov/pubmed/24036228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamem.2013.08.020
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