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Overexpression of adenosine kinase in cortical astrocytes generates focal neocortical epilepsy in mice: Laboratory investigation

OBJECT: New experimental models and diagnostic methods are needed to better understand the pathophysiology of focal neocortical epilepsies in a search for improved epilepsy treatment options. We hypothesized that a focal disruption of adenosine homeostasis in the neocortex might be sufficient to tri...

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Main Authors: Shen, Hai-Ying, Sun, Hai, Hanthorn, Marissa M., Zhi, Zhongwei, Lan, Jing-Quan, Poulsen, David J., Wang, Ruikang K., Boison, Detlev
Formato: Artigo
Idioma:Inglês
Publicado: 2013
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3943589/
https://ncbi.nlm.nih.gov/pubmed/24266544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3171/2013.10.JNS13918
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