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Membrane damage-induced vesicle–vesicle fusion of dysferlin-containing vesicles in muscle cells requires microtubules and kinesin

Mutations in the dysferlin gene resulting in dysferlin-deficiency lead to limb-girdle muscular dystrophy 2B and Myoshi myopathy in humans. Dysferlin has been proposed as a critical regulator of vesicle-mediated membrane resealing in muscle fibers, and localizes to muscle fiber wounds following sarco...

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Библиографические подробности
Главные авторы: McDade, Joel R., Michele, Daniel E.
Формат: Artigo
Язык:Inglês
Опубликовано: Oxford University Press 2014
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3943514/
https://ncbi.nlm.nih.gov/pubmed/24203699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddt557
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