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Thalassemic erythrocytes release microparticles loaded with hemichromes by redox activation of p72Syk kinase

High counts of circulating microparticles, originated from the membrane of abnormal erythrocytes, have been associated with increased thrombotic risk in hemolytic disorders. Our studies indicate that in thalassemia intermedia patients the number of circulating microparticles correlates with the capa...

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Detalhes bibliográficos
Main Authors: Ferru, Emanuela, Pantaleo, Antonella, Carta, Franco, Mannu, Franca, Khadjavi, Amina, Gallo, Valentina, Ronzoni, Luisa, Graziadei, Giovanna, Cappellini, Maria Domenica, Turrini, Francesco
Formato: Artigo
Idioma:Inglês
Publicado em: Ferrata Storti Foundation 2014
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3943323/
https://ncbi.nlm.nih.gov/pubmed/24038029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2013.084533
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