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Divergence of zebrafish and mouse lymphatic cell fate specification pathways

In mammals, the homeodomain transcription factor Prox1 acts as the central regulator of lymphatic cell fate. Its restricted expression in a subset of cardinal vein cells leads to a switch towards lymphatic specification and hence represents a prerequisite for the initiation of lymphangiogenesis. Mur...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: van Impel, Andreas, Zhao, Zhonghua, Hermkens, Dorien M. A., Roukens, M. Guy, Fischer, Johanna C., Peterson-Maduro, Josi, Duckers, Henricus, Ober, Elke A., Ingham, Philip W., Schulte-Merker, Stefan
Format: Artigo
Sprache:Inglês
Veröffentlicht: Company of Biologists 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3943180/
https://ncbi.nlm.nih.gov/pubmed/24523456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.105031
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