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Structure of Mycobacterium tuberculosis nucleoside diphosphate kinase R80N mutant in complex with citrate
The crystal structure of the wild-type nucleoside diphosphate kinase from Mycobacterium tuberculosis at 2.6 Å resolution revealed that the intersubunit salt bridge Arg80–Asp93 contributes to the thermal stability of the hexamer (T (m) = 76°C). On mutating Asp93 to Asn to break the salt bridge, the t...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
International Union of Crystallography
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3943099/ https://ncbi.nlm.nih.gov/pubmed/24419614 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S2053230X13034134 |
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