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Structural mechanism of DNA recognition by the p202 HINa domain: insights into the inhibition of Aim2-mediated inflammatory signalling

The HIN-200 family of proteins play significant roles in inflammation-related processes. Among them, AIM2 (absent in melanoma 2) and IFI16 (γ-interferon-inducible protein 16) recognize double-stranded DNA to initiate inflammatory responses. In contrast, p202, a mouse interferon-inducible protein con...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Li, He, Wang, Jue, Wang, Jie, Cao, Lu-Sha, Wang, Zhi-Xin, Wu, Jia-Wei
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: International Union of Crystallography 2013
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3943098/
https://ncbi.nlm.nih.gov/pubmed/24419611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S2053230X1303135X
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