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Studies on mutant human insulin genes: identification and sequence analysis of a gene encoding [SerB24]insulin.

Both alleles of the insulin gene of a patient with mild diabetes [maturity-onset-diabetes-of-the-young (MODY)-type syndrome] associated with hyperinsulinemia have been cloned, and the sequences have been determined. One allele contained a mutation (single nucleotide transition) in the coding sequenc...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Haneda, M, Chan, S J, Kwok, S C, Rubenstein, A H, Steiner, D F
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1983
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC394298/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6312455/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.80.20.6366
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