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Role of Insulin Resistance in the Pathogenesis and Development of Type 2 Diabetes in WBN/Kob-Lepr(fa) Rats
WBN/Kob-Lepr(fa) (fa/fa) rats have been identified as a new animal model of type 2 diabetes (T2DM), as they are characterized by impaired pancreatic insulin secretion and severe insulin resistance. Our previous study demonstrated impaired insulin secretion and its involvement in hyperglycemia in fa/...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Japanese Society of Veterinary Science
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3942958/ https://ncbi.nlm.nih.gov/pubmed/23892462 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1292/jvms.13-0230 |
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