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Functional immunoglobulin M production after transfection of cloned immunoglobulin heavy and light chain genes into lymphoid cells.

The rearranged immunoglobulin heavy (mu) and light (kappa) chain genes cloned from the Sp6 hybridoma cell line producing immunoglobulin M specific for the hapten 2,4, 6-trinitrophenyl were inserted into the transfer vector pSV2-neo and introduced into various plasmacytoma and hybridoma cell lines. T...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Ochi, A, Hawley, R G, Hawley, T, Shulman, M J, Traunecker, A, Köhler, G, Hozumi, N
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1983
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC394295/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6312453/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.80.20.6351
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