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Soluble T Cell Receptor Vβ Domains Engineered for High-Affinity Binding to Staphylococcal or Streptococcal Superantigens
Staphylococcus aureus and group A Streptococcus secrete a collection of toxins called superantigens (SAgs), so-called because they stimulate a large fraction of an individual’s T cells. One consequence of this hyperactivity is massive cytokine release leading to severe tissue inflammation and, in so...
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
MDPI
2014
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| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3942751/ https://ncbi.nlm.nih.gov/pubmed/24476714 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/toxins6020556 |
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